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PD153035 hydrochloride

CAS No. 183322-45-4

PD153035 hydrochloride ( AG-1517 )

Catalog No. M12831 CAS No. 183322-45-4

PD153035 hydrochloride (ZM 252868; AG 1517) is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect against PGDFR, FGFR, CSF-1, InsR and Src.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 56 In Stock
25MG 113 In Stock
50MG 221 In Stock
100MG 375 In Stock
500MG 853 In Stock
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Biological Information

  • Product Name
    PD153035 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    PD153035 hydrochloride (ZM 252868; AG 1517) is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect against PGDFR, FGFR, CSF-1, InsR and Src.
  • Description
    PD153035 hydrochloride (ZM 252868; AG 1517) is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect against PGDFR, FGFR, CSF-1, InsR and Src.
  • Synonyms
    AG-1517
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR; EGFR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    183322-45-4
  • Formula Weight
    396.67
  • Molecular Formula
    C16H15BrClN3O2
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 0.5 mg/mL (1.26 mM)
  • SMILES
    COc(c1)c(OC)cc2c1ncnc2Nc3cc(Br)ccc3.Cl
  • Chemical Name
    N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fry DW, et al. Science. 1994, 265(5175), 1093-1095.
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